qoxD [2017-04-24 15:34:12]

cytochrome aa3 quinol oxidase (subunit IV)

Locus: BSU38140

Isoelectric point: 5.94

Molecular weight: 13.55 kDa

Protein length: 124 aa

Gene length: 372 bp

Function: respiration

Product: cytochrome aa3 quinol oxidase (subunit IV)

Essential: no

E.C.: 1.10.3.-

Synonyms: ipa-40d

Genomic Context

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Categories containing this gene/protein

• Metabolism → Electron transport and ATP synthesis → Respiration → Terminal oxidases
• Groups of genes → Membrane proteins

This gene is a member of the following regulons

• stringent response, CitB regulon (putative)

Gene

Coordinates: 3,914,315 → 3,914,689

The protein

Catalyzed reaction/ biological activity

• Ubiquinol-8 O₂ = Ubiquinone-8 H₂O (according to Swiss-Prot)

Protein family

• cytochrome c oxidase bacterial subunit 4 family (according to Swiss-Prot)

Localization

• cell membrane (according to Swiss-Prot)

Expression and Regulation

Operons

• Genes: qoxA-qoxB-qoxC-qoxD
  Description: PubMed

  Regulatory mechanism

  • stringent response: negative regulation, in stringent response
  • CitB: mRNA binding, in CitB regulon

  Regulation

  • RelA dependent downregulation (Class I) during stringent response PubMed

  Additional information

  • the presence of an iron-responsive element bound by CitB between feuA and feuB suggests iron-dependent regulation by CitB PubMed

References

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